Let’s clear up some misinformation about Testosterone Therapy, shall we?
A recent smear piece was shown to me by one of my patients; a Sunday morning ‘news’ show, paraded an obese male whom was unfortunate enough to have suffered a stroke. The show then went on to state, that he ( the patient) blamed this episode on receiving Testosterone Replacement Therapy (TRT).
I don’t not know the specifics of this patient’s case, however, with regards to TRT, it is actually proven that low Testosterone levels which will increase your risk of stroke… Not Testosterone Replacement Therapy . This is truly… FAKE NEWS!
Recent studies from The Cleveland Clinic suggest that Testosterone replacement does not increase cardiovascular risk. Particularly aging, tobacco use, arterial hypertension, diabetes mellitus, elevated triglycerides, and cardiovascular disease itself have been associated with increased prevalence of stroke, all which can be improved with TRT, (especially when executed with diet, exercise and close monitoring-as I suggest to all of my patients).
There has been recent focus on the role of both endogenous testosterone and testosterone therapy in atherosclerosis particularly with regards to ischemic heart disease and cerebrovascular disease. Epidemiological studies suggest that both low and high endogenous testosterone levels may contribute to atherosclerosis and clinical cardiac and cerebrovascular events in men.
It must be noted however, that, those men with lower testosterone had significantly higher BMI, greater waist circumference, higher prevalence of diabetes mellitus and hypertension, giving them an increase risk of stroke!
In fact lower endogenous plasma testosterone was associated with incident clinical stroke events, WHEREAS, CORRECTED ( OR TREATED) TESTOSTERONE LEVELS IS NOT!
After controlling for atherosclerotic risk factors, there WAS NO association between endogenous testosterone and incidence in clinical stroke or ischemic brain changes in community-dwelling men.
(Stroke. 2016;47:2682-2688. DOI: 10.1161/STROKEAHA.116.014088.)